• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文OA文献 >A randomised controlled trial of cognitive behaviour therapy versus non-directive reflective listening for young people at ultra high risk of developing psychosis: the detection and evaluation of psychological therapy (DEPTh) trial
【2h】

A randomised controlled trial of cognitive behaviour therapy versus non-directive reflective listening for young people at ultra high risk of developing psychosis: the detection and evaluation of psychological therapy (DEPTh) trial

机译：患有精神病极高风险的年轻人的认知行为治疗与非定向反射听觉的随机对照试验：心理治疗（DEPTh）试验的检测和评估

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Intervention trials for young people at ultra high risk (UHR) for psychosis have shown cognitive behaviour therapy (CBT) to have promising effects on treating psychotic symptoms but have not focused on functional outcomes. We hypothesized that compared to an active control, CBT would: (i) reduce the likelihood of, and/or delay, transition to psychosis; (ii) reduce symptom severity while improving social functioning and quality of life, whether or not transition occurred. Method: This was a single-blind randomised controlled trial for young people at UHR for psychosis comparing CBT to an active control condition, Non Directive Reflective Listening (NDRL), both in addition to standard care, with a 6 month treatment phase and 12 months of follow-up. Statistical analysis is based on intention-to-treat and used random effect models to estimate treatment effects common to all time-points. Results: Fifty-seven young people (mean age = 16.5 years) were randomised to CBT (n = 30) or NDRL (n = 27). Rate of transition to psychosis was 5%; the 3 transitions occurred in the CBT condition (baseline, 2 months, 5 months respectively). The NDRL condition resulted in a significantly greater reduction in distress associated with psychotic symptoms compared to CBT (treatment effect = 36.71, standard error = 16.84, p = 0.029). There were no significant treatment effects on frequency and intensity of psychotic symptoms, global, social or role functioning. Conclusion: Our sample was higher functioning, younger and experiencing lower levels of psychotic like experiences than other trials. The significantly better treatment effect of NDRL on distress associated with psychotic symptoms supports the recommendations for a stepped-care model of service delivery. This treatment approach would accommodate the younger UHR population and facilitate timely intervention.
机译：背景：针对精神病的超高风险青年（UHR）的干预试验表明，认知行为疗法（CBT）在治疗精神病性症状方面具有可喜的效果，但并未关注功能结局。我们假设与主动控制相比，CBT将：（i）减少患精神病的可能性和/或减少其过渡到精神病的可能性； （ii）减轻症状严重程度，同时改善社会功能和生活质量，无论是否发生过渡。方法：这是一项针对UHR精神病年轻人的单盲随机对照试验，将CBT与一种主动控制条件，非定向反射听力（NDRL），除了标准护理外，均进行了6个月的治疗和12个月的治疗的后续行动。统计分析基于意向治疗，并使用随机效应模型来估计所有时间点共有的治疗效果。结果：五十七名年轻人（平均年龄= 16.5岁）被随机分为CBT（n = 30）或NDRL（n = 27）。转变为精神病的比率为5％；在CBT条件下发生了3个转换（分别是基线，2个月，5个月）。与CBT相比，NDRL条件导致与精神病症状相关的困扰明显减少（治疗效果= 36.71，标准误= 16.84，p = 0.029）。对精神病症状的频率和强度，整体，社会或角色功能没有明显的治疗作用。结论：我们的样本比其他试验具有更高的功能，更年轻的精神病体验。 NDRL对与精神病症状相关的困扰的治疗效果明显更好，这支持了对服务提供的分步护理模型的建议。这种治疗方法将适应年轻的UHR人群并促进及时干预。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号